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The five-point scale is defined as follows: 0 no symptoms; 1 slight; 2 moderate; 3 marked; 4 very marked. Scores for erthema, induration was passiert wenn ne frau viagra nimmt six desquamation are totalled. LPSI ranges from 0 to 12 with the higest score representing the more severe disease state. In general, the volunteers treated with topical placebo have little or no response passiiert treatment, whereas the volunteers treated with a topical pharmaceutical composition of the present invention show positive trends in pfizer vgr 100 wirkung viagra disease state or condition index at the conclusion of the study. In particular, the topical pharmaceutical composition of the present invention is obviously effective on most patients in the treatment group. No visible side-effects are observed. EXAMPLE 10.

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Suitable physical measurements include skinfold caliper measurements or A- andor B-mode ultrasound measurements of the thickness of the subcutaneous fat layer overlying the upper arm. Suitable biological measurements include blood levels of insulin and glucose in body fluids, tissues or organs compared to pre-treatment levels. Other measurements include, but are not limited to, body weight and blood pressure as well as ADME (absorption, distribution, metabolism and excretion) measurements. Information recorded for each patient includes age (years), gender, height (cm), family history of condition (yesno), motivation rating (somemoderategreat) and number and type of previous treatment regimens for the indicated condition. Volunteers taking part in this study are adults aged 18 to 65 years and roughly an equal number of males and females participate in the study.

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